Floating and Sustained-Release Characteristics of Effervescent Tablets Prepared with a Mixed Matrix of Eudragit L-100-55 and Eudragit E PO
نویسندگان
چکیده
منابع مشابه
Floating and sustained-release characteristics of effervescent tablets prepared with a mixed matrix of Eudragit L-100-55 and Eudragit E PO.
The aim of this study was to evaluate the influence of Na-bicarbonate as an effervescent agent on the floating and sustained-release characteristics in 0.1 M HCl of tablets made of Eudragit E PO (EE) and/or Eudragit L-100-55 (EL) as matrix formers at different EE:EL weight ratios: 0:100, 25:75, 50:50, 75:25, and 100:0. The tablets were made by direct compression utilizing metronidazole as a mod...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2011
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.59.155